P-017

Phenobarbital-D₅ (side chain) solution

(deuterium label on side chain), 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₁₂D₅H₇N₂O₃
• Numero CAS: 73738-05-3
• Peso molecolare: 237.27
• Numero MDL: MFCD00145091
• Codice UNSPSC: 41116107
• ID PubChem: 329820020
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Livello qualitativo: 300
• Stato: liquid
• Caratteristiche: Snap-N-Spike^®/Snap-N-Shoot^®
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• Concentrazione: 1.0 mg/mL in methanol
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: forensics and toxicology
• Formato: single component solution
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [2H]C([2H])([2H])C([2H])([2H])C1(C(=O)NC(=O)NC1=O)c2ccccc2
• InChI: 1S/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17)/i1D3,2D2; DDBREPKUVSBGFI-ZBJDZAJPSA-N

Descrizione

Descrizione generale

An internal standard suitable for quantitation of phenobarbital levels in GC/MS or LC/MS applications for clinical toxicology, urine drug testing, or forensic analysis. Phenobarbital is a barbiturate used to treat all epileptic seizure types except for absence seizures. Phenobarbital is the oldest and most widely used anticonvulsant.

Applicazioni

• Mass spectrometry imaging standard: Phenobarbital-D5 is used in mass spectrometry imaging by desorption electrospray ionization, functioning as a critical internal standard to enhance the accuracy of spatial distribution analyses in various tissues. This application underlines its significance in pharmaceutical and biochemical research (Perez and Ifa, 2021).
• Forensic application in drug-facilitated crimes: Employed in a validated UHPLC-HRMS method, Phenobarbital-D5 is instrumental in the determination of barbiturates in hair samples, playing a vital role in the investigation of drug-facilitated sexual assaults. This demonstrates its utility as a stable isotope-labeled compound in forensic toxicology (Wen et al., 2022).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H301 + H311 + H331,H370
• Consigli di prudenza: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organi bersaglio: Eyes
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 49.5 °F - closed cup
• Punto d’infiammabilità (°C): 9.7 °C - closed cup