860829P
Avanti
18:0(2R-OH) Ceramide
Avanti Research™ - A Croda Brand 860829P, powder
Sinonimo/i:
N-(2′-(R)-hydroxystearoyl)-D-erythro-sphingosine
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About This Item
Formula empirica (notazione di Hill):
C36H71NO4
Numero CAS:
Peso molecolare:
581.95
Codice UNSPSC:
12352211
NACRES:
NA.25
Prodotti consigliati
Stato
powder
Confezionamento
pkg of 1 × 5 mg (860829P-5mg)
Produttore/marchio commerciale
Avanti Research™ - A Croda Brand 860829P
Tipo di lipide
sphingolipids
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Stringa SMILE
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCCC)=O)CO
Categorie correlate
Descrizione generale
18:0(2R-OH) Ceramide is a unique ceramide containing 18C long chain base fatty acid (stearic acid)-with 2′-hydroxyl group in R configuration.
Azioni biochim/fisiol
18:0(2R-OH) Ceramide is essential for maintaining membrane fluidity.
Confezionamento
5 mL Amber Glass Screw Cap Vial (860829P-5mg)
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Jennifer E Kyle et al.
The Analyst, 141(5), 1649-1659 (2016-01-07)
Understanding how biological molecules are generated, metabolized and eliminated in living systems is important for interpreting processes such as immune response and disease pathology. While genomic and proteomic studies have provided vast amounts of information over the last several decades
Ana B Herrero et al.
Cancer research, 68(23), 9779-9787 (2008-12-03)
PM02734 is a novel synthetic antitumor drug that is currently in phase I clinical trials. To gain some insight into its mode of action, we used the yeast Saccharomyces cerevisiae as a model system. Treatment of S. cerevisiae with PM02734
Nathan L Alderson et al.
Journal of lipid research, 50(6), 1203-1208 (2009-01-28)
Sphingolipids are ubiquitous components of eukaryotic cells that regulate various cellular functions. In many cell types, a fraction of sphingolipids contain 2-hydroxy fatty acids, produced by fatty acid 2-hydroxylase (FA2H), as the N-acyl chain of ceramide [hydroxyl fatty acid (hFA)-sphingolipids].
Hiroko Hama
Biochimica et biophysica acta, 1801(4), 405-414 (2009-12-23)
2-Hydroxy fatty acids (hFA) are important components of a subset of mammalian sphingolipids. The presence of hFA in sphingolipids is best described in the nervous system, epidermis, and kidney. However, the literature also indicates that various hFA-sphingolipids are present in
Zdzislaw M Szulc et al.
Bioorganic & medicinal chemistry, 18(21), 7565-7579 (2010-09-21)
A straightforward method for the simultaneous preparation of (2S,3R,2'R)- and (2S,3R,2'S)-2'-hydroxy-ceramides (2'-OHCer) from (2S,3R)-sphingosine acetonide precursors and racemic mixtures of 2-hydroxy fatty acids (2-OHFAs) is described. The obtained 2'-OH-C4-, -C6-, -C12-, -C16-Cer and 2'-OH-C6-dhCer pairs of diastereoisomers were characterized thoroughly
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