850346C

14:1 (Δ9-Cis) PC

1,2-dimyristoleoyl-sn-glycero-3-phosphocholine, chloroform

• Sinonimo/i: 1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-phosphocholine; PC(14:1(9Z)/14:1(9Z))
• Formula empirica (notazione di Hill): C₃₆H₆₈NO₈P
• Numero CAS: 56750-90-4
• Peso molecolare: 673.90
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Stato: liquid
• Confezionamento: pkg of 1 × 2.5 mL (850346C-25mg); pkg of 2 × 4 mL (850346C-200mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 850346C
• Concentrazione: 10 mg/mL (850346C-25mg); 25 mg/mL (850346C-200mg)
• Tipo di lipide: cardiolipins; phospholipids
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Applicazioni

14:1 (Δ9-Cis) PC has been used in the liposome preparation. It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.

Azioni biochim/fisiol

Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells. PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia. Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Confezionamento

5 mL Clear Glass Sealed Ampule (850346C-200mg)

5 mL Clear Glass Sealed Ampule (850346C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372
• Consigli di prudenza: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Organi bersaglio: Liver,Kidney, Respiratory system
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): does not flash
• Punto d’infiammabilità (°C): does not flash