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Documenti fondamentali

810130P

Avanti

16:0-06:0 NBD PC

Avanti Research™ - A Croda Brand 810130P, powder

Sinonimo/i:

1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine

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About This Item

Formula empirica (notazione di Hill):
C36H62N5O11P
Numero CAS:
91992-01-7
Peso molecolare:
771.88
Numero MDL:
MFCD00067469
Codice UNSPSC:
12352211
NACRES:
NA.25

Saggio

>99% (TLC)

Stato

powder

Confezionamento

pkg of 1 × 1 mg (810130P-1mg)
pkg of 5 × 1 mg (810130P-5mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 810130P

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Descrizione generale

16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) is a fluorescent analogue of phosphatidylcholine.

Applicazioni

16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) has been used in NBD-phospholipid translocation assay. It may be used as a molecular fluorescent marker to label lipids during the friction tests, as substrate for enzyme substrate specificity determination and in the preparation of small unilamellar vesicles.

Azioni biochim/fisiol

16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) acts as a potential fluorescent probe. It is used for the quantification of the soluble and membrane-bound phospholipase A2 (PLA2) activity. 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) derivatives are widely used as fluorescent analogs of native lipids in biological and model membranes to study a variety of processes.

Confezionamento

5 mL Amber Glass Screw Cap Vial (810130P-1mg)
5 mL Amber Glass Screw Cap Vial (810130P-5mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

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Certificati d'analisi (COA)

Lot/Batch Number

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Effects of fluorescent probe NBD-PC on the structure, dynamics and phase transition of DPPC. A molecular dynamics and differential scanning calorimetry study
Loura L, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(2), 491-501 (2008)
In vitro analysis of the Staphylococcus aureus lipoteichoic acid synthase enzyme using fluorescently labeled lipids
Karatsa-Dodgson MW, et al.
Journal of Bacteriology, 192(20), 5341-5349 (2010)
The use of C6-NBD-PC for assaying phospholipase A2-activity: scope and limitations
Meyuhas D, et al.
Biochimica et Biophysica Acta, Lipids and Lipid Metabolism, 1124(3), 223-232 (1992)
Role of the biomolecular interactions in the structure and tribological properties of synovial fluid
Mirea DA, et al.
Tribology International, 59(3), 302-311 (2013)
Lenka Grycova et al.
PloS one, 7(10), e48437-e48437 (2012-11-03)
TRPV1 is a nonselective cation channel that integrates wide range of painful stimuli. It has been shown that its activity could be modulated by intracellular ligands PIP2 or calmodulin (CaM). The detailed localization and description of PIP2 interaction sites remain
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