330678
Avanti
SM ELISA (Clear)
Avanti Research™ - A Croda Brand
Sinonimo/i:
SM ELISA, Brain Sphingomyelin ELISA Snoopers™, Clear, for use in absorbance applications
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About This Item
Prodotti consigliati
Stato
liquid
Produttore/marchio commerciale
Avanti Research™ - A Croda Brand
Confezionamento
1 ea of 1 × (ELISA strip packaged in foil pouch)
Condizioni di spedizione
wet ice
Temperatura di conservazione
2-8°C
Descrizione generale
Avanti Lipid Snoopers™ are lipid microarrays useful in semi-quantitative measurements. These snoopers are relatively stable and provide a higher sensitivity compared to the conventional enzyme-linked immunosorbent assay (ELISA) methods. Sphingomyelin (SM) is a sphingolipid present in central nervous system as a component of the myelin sheath and neuronal cells. It is synthesized from ceramide in Golgi. Acid sphingomyelinase (aSMase) degrades SM.
ELISA Snoopers™ are 8-well strips pre-coated with a single high-quality lipid species. They can be used to investigate protein-lipid interactions, and characterize and titrate lipid binding proteins. This format provides the following advantages:
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
- quantitative lipid-protein binding studies
- assemble a 96-well plate using only the lipids of interest for binding studies
- flexibility - use 8 to 96 wells, and 1 to 12 lipids as needed.
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
Azioni biochim/fisiol
Sphingomyelin (SM) participates in the inflammatory process and signalling pathways. It is a crucial regulator for myelin integrity, axon maturation, cognition and brain development. The SM to ceramide ratio is crucial, as high ceremide levels are implicated in depression. Altered levels of sphingomyelin due to sphingomyelinase deficiency results in Niemann–Pick disease.
Confezionamento
ELISA Strip Packaged in Foil Pouch (330678-1EA)
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Snoopers is a trademark of Avanti Polar Lipids, LLC
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
No data available
Punto d’infiammabilità (°C)
No data available
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Sphingolipid metabolism in neural cells
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1758(12), 1978-1994 (2006)
Sphingolipids: membrane microdomains in brain development, function and neurological diseases
Open Biology, 7(5), 170069-170069 (2017)
Sphingomyelin in brain and cognitive development: preliminary data
eNeuro (2019)
Avanti lipid tools: connecting lipids, technology, and cell biology
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1841(8), 1038-1048 (2014)
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