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W355690

Sigma-Aldrich

Isopropyl myristate

≥98%

Sinonimo/i:

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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About This Item

Formula condensata:
CH3(CH2)12COOCH(CH3)2
Numero CAS:
Peso molecolare:
270.45
Numero FEMA:
3556
Beilstein:
1781127
Numero CE:
N° CoE:
386
Numero MDL:
Codice UNSPSC:
12164502
ID PubChem:
Numero Flavis:
9.105
NACRES:
NA.21

Origine biologica

synthetic

Livello qualitativo

Grado

Fragrance grade
Halal
Kosher

agenzia

follows IFRA guidelines

Conformità normativa

EU Regulation 1223/2009

Saggio

≥98%

Indice di rifrazione

n20/D 1.434 (lit.)

P. eboll.

193 °C/20 mmHg (lit.)

Punto di fusione

~3 °C (lit.)

Densità

0.85 g/mL at 25 °C (lit.)

applicazioni

flavors and fragrances

Documentazione

see Safety & Documentation for available documents

Allergene alimentare

no known allergens

Allergene in fragranze

no known allergens

Organolettico

faint; fatty; oily

Stringa SMILE

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
AXISYYRBXTVTFY-UHFFFAOYSA-N

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Descrizione generale

Isopropyl myristate is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It is also used as a flavoring agent in the food industry.

Applicazioni


  • Development of Nanostructured Lipid Carrier-Loaded Flavonoid-Enriched Zingiber officinale.: This research develops nanostructured lipid carriers for flavonoids derived from Zingiber officinale, employing Isopropyl myristate to stabilize these carriers and improve bioactive compound delivery (Shazwani SS et al., 2024).

  • Comparative evaluation of physical and chemical enhancement techniques for transdermal delivery of linagliptin.: The study compares various enhancement methods for transdermal drug delivery, including the use of Isopropyl myristate, highlighting its effectiveness in permeation enhancement techniques (Karve T et al., 2024).

  • Optimization of Conditions of Zanthoxylum Alkylamides Liposomes by Response Surface Methodology and the Absorption Characteristics of Liposomes in the Caco-2 Cell Monolayer Model.: This research optimizes liposome formulations containing Zanthoxylum alkylamides, with Isopropyl myristate being crucial in liposome stability and absorption characteristics (Wang R et al., 2024).

Azioni biochim/fisiol

Odor at 1.0%
Taste at 10 ppm

Esclusione di responsabilità

For R&D or non-EU Food use. Not for retail sale.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

awg

Punto d’infiammabilità (°F)

>302.0 °F

Punto d’infiammabilità (°C)

> 150 °C

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Handbook of Preservatives, 425-425 (2004)
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
T N Engelbrecht et al.
Skin pharmacology and physiology, 25(4), 200-207 (2012-05-23)
In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol, palmitic acid and cholesterol sulfate
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized

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