QBD10406

MAL-dPEG^®₄-(m-dPEG^®₁₂)₃

• Sinonimo/i: Polyethylene glycol
• Formula empirica (notazione di Hill): C₁₀₆H₂₀₂N₆O₅₀
• Numero CAS: 1334178-05-0
• Peso molecolare: 2360.75
• Codice UNSPSC: 51171641
• ID PubChem: 329823926
• NACRES: NA.22

Proprietà

• Saggio: >90%
• Stato: solid or viscous liquid
• Impiego in reazioni chimiche: reactivity: thiol reactive; reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: sulfhydryl reactive
• Architettura del polimero: shape: branched; functionality: monofunctional
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=C(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)NC(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O
• InChI: 1S/C106H202N6O50/c1-120-24-27-128-40-43-136-54-57-142-66-69-148-78-81-154-90-93-157-87-84-151-75-72-145-63-60-139-51-48-133-37-32-125-21-12-108-100(114)7-17-160-96-106(111-103(117)10-16-123-30-35-131-46-47-132-36-31-124-20-11-107-99(113)6-15-112-104(118)4; NDEZSFRLBSRIHD-UHFFFAOYSA-N

Descrizione

Caratteristiche e vantaggi

MAL-dPEG^®₄-(m-dPEG^®₁₂)₃ is a branched dPEG^® reagent which is highly useful for protein and peptide modification to increase hydrodynamic volume and serum half-life and to greatly reduce the immunogenicity of the modified peptide or protein. This dPEG^® product consists of a linear "tail" with a reactive group, a tris core to provide branching, and methoxy-terminated dPEG^® branches. The numbers following dPEG^® are the exact number of repeat units in the linear chain. All of these dPEG^® products are hydrophilic, non-immunogenic, single molecular weight compounds. The maleimide functional group reacts rapidly and specifically with free sulfhydryls in aqueous media at pH 6.5-7.5.

Note legali

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable