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M70800

Sigma-Aldrich

3-Methyl-1-phenyl-2-pyrazoline-5-one

99%, for peptide synthesis

Sinonimo/i:

Edaravone, 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

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About This Item

Formula empirica (notazione di Hill):
C10H10N2O
Numero CAS:
89-25-8
Peso molecolare:
174.20
Beilstein:
609575
Numero CE:
201-891-0
Numero MDL:
MFCD00003138
Codice UNSPSC:
12352005
ID PubChem:
24897140
NACRES:
NA.22

Nome del prodotto

3-Methyl-1-phenyl-2-pyrazoline-5-one, 99%

Livello qualitativo

200

Saggio

99%

Stato

powder, crystals or chunks

P. ebollizione

287 °C/265 mmHg (lit.)

Punto di fusione

126-128 °C (lit.)

applicazioni

peptide synthesis

Stringa SMILE

CC1=NN(C(=O)C1)c2ccccc2

InChI

1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3
QELUYTUMUWHWMC-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

3-Methyl-1-phenyl-2-pyrazoline-5-one may be used:
  • As a reagent for the detection of reducing carbohydrates by ESI/MALDI-MS.
  • To improve the sensitivity of reducing mono- and oligo-saccharides for their subsequent determination using capillary zone electrophoresis.
  • For the precolumn derivatization of the monosaccharide components of Salvia miltiorrhiza, liguspyragine hydrochloride, and glucose injection prior to their analysis by high performance liquid chromatography (HPLC).

Reagent for detection of reducing carbohydrates by ESI/MALDI -MS.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H319

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
BCCG2592
BCCF3234
BCCC1326
MKCJ2163
BCBZ5157

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Fa-Huan Ge et al.
Journal of analytical methods in chemistry, 2017, 9245620-9245620 (2017-05-11)
Salvia miltiorrhiza, liguspyragine hydrochloride, and glucose injection (SLGI) was made of Salvia miltiorrhiza Bge., liguspyragine hydrochloride, glucose, and glycerin. There were many kinds of monosaccharide components in SLGI, which might be from the raw material and Salvia miltiorrhiza Bge. Separation
Hidehiko Nakagawa et al.
Bioorganic & medicinal chemistry letters, 16(23), 5939-5942 (2006-09-26)
We synthesized various 3-methyl-1-phenyl-5-pyrazolone (edaravone) derivatives and evaluated their oxidation potential and hydroxyl radical scavenging activity. It was found 3-methyl-1-(pyridin-2-yl)-5-pyrazolone had a much higher ability to scavenge the radical than did edaravone itself. Its efficient radical scavenging activity was assumed
Xin-Gang Du et al.
Journal of natural products, 73(8), 1422-1426 (2010-08-04)
Two new dimeric xanthone O-glycosides, puniceasides A (1) and B (2), a new trimeric O-glycoside, puniceaside C (3), and two new trimeric C-glycosides, puniceasides D (4) and E (5), together with 12 known xanthones were isolated from the entire plant
Xian-Wen Yang et al.
Journal of natural products, 70(4), 521-525 (2007-03-09)
Six new mixed lignan-neolignans and 20 known compounds were isolated from the whole plant of Tarenna attenuata. By analysis of physical and spectroscopic data, the structures of the new compounds were elucidated as (1R,5R,6R)-6-{4-O-[2-(1-(4-hydroxy-3-methoxyphenyl))glycerol]-3,5-dimethoxyphenyl}-3,7-dioxabicyclo[3.3.0]octan-2-one (1), 5' '-methoxyhedyotisol A (2), 4'
Konstantin Chegaev et al.
Journal of medicinal chemistry, 52(2), 574-578 (2008-12-31)
A new series of polyvalent drugs obtained by joining edaravone with NO-donor moieties is described. All compounds display high antioxidant power together with NO-dependent vasodilator properties. The analysis of a number of molecular descriptors shows that the antioxidant activity, which
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