914169
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) dimethacrylate
average Mn ~12,500
Sinonimo/i:
PEG-PPG-PEG, Pluronic Dimethacrylate, Pluronic F-127 dimethacrylate
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About This Item
Prodotti consigliati
Forma fisica
powder
Livello qualitativo
PM
average Mn ~12,500
Colore
off-white to yellow
Temperatura di conservazione
−20°C
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Applicazioni
Poloxamers are nonionic, triblock copolymers containg a central hydrophobic chain of poly(propylene glycol) (PPG) and two terminal hydrophilic chains of poly(ethylene glycol) (PEG). Due to their amphiphilic structure, poloxamer solutions feature temperature dependent self-assembling and thermo-gelling behavior. Concentrated aqueous solutions of poloxamers are liquid at low temperature and form a gel at higher temperature, in a reversible process. This characteristic has allowed for these materials to be used as drug carriers for most routes of administration including oral, topical, intranasal, ocular, and parenteral. Methacrylate-modified derivatives are most commonly used as thermosensitive hydrogels for drug delivery and 3D bioprinting applications. After casting or printing, the material can be crosslinked to preserve the hydrogel structure.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization.
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Mesenchymal stem cells (MSCs) represent a very attractive cell source for tissue engineering applications aiming at the generation of artificial bone substitutes. The use of three-dimensional bioprinting technologies has the potential to improve the classical tissue engineering approach because bioprinting
Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization.
Soft Materials, 7, 4928-4937 (2011)
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