907286

H-L-Photo-Proline hydrochloride

≥95%, for peptide synthesis

• Sinonimo/i: (S)-1,2,5-Triazaspiro[2.4]hept-1-ene-6-carboxylic acid, Diazirine amino acid, Photo-Pro, Photo-crosslinking amino acid, Photoprobe building block
• Formula empirica (notazione di Hill): C₅H₈ClN₃O₂
• Peso molecolare: 177.59
• Codice UNSPSC: 12352101
• NACRES: NA.22

Proprietà

• product name: H-L-Photo-Proline hydrochloride, ≥95%
• Saggio: ≥95%
• Forma fisica: powder
• Impiego in reazioni chimiche: reaction type: solution phase peptide synthesis
• applicazioni: peptide synthesis
• Temperatura di conservazione: −20°C

Descrizione

Applicazioni

H-L-Photo-Proline HCl is a diazirine-containing proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907324.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Altre note

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable