901708

Thiol-poly(ethylene glycol)-b-poly(ε-caprolactone)

PEG average M_n 5000, PCL average M_n 5000

• Formula condensata: C₅H₁₀S₂O[C₂H₄O]n[C₆H₁₀O₂]mH
• Codice UNSPSC: 51171641
• NACRES: NA.23

Proprietà

• Forma fisica: powder or solid
• PM: PCL average M_n 5000; PEG average M_n 5000
• Colore: white to off-white
• Ind. polidispersione: ≤1.3 (By GPC)
• Temperatura di conservazione: −20°C

Descrizione

Applicazioni

Thiol-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The thiol functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P301 + P312 + P330
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable