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Key Documents

900393

Sigma-Aldrich

Folate-PEG2000-COOH

average Mn 2,000

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About This Item

Formula condensata:
C19H19N8O5(C2H4O)nC2H3O2
Codice UNSPSC:
51171641
NACRES:
NA.23

Forma fisica

powder

Livello qualitativo

PM

average Mn 2,000

Temp. transizione

Tm 39-49 °C

Temperatura di conservazione

−20°C

Applicazioni

The folate end group may be used for target-specific cellular uptake of drug delivery vehicles and the carboxylate group can be used for further conjugation to make drug conjugates, polymeric nanoparticles, or folate targeting liposomes.

Note legali

Product of JenKem Technology.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Folic acid British Pharmacopoeia (BP) Reference Standard

BP937

Folic acid

Folic acid BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥97%

Sigma-Aldrich

F8758

Folic acid

DSPE-PEG(2000) Amine Avanti Research™ - A Croda Brand 880128C

Avanti

880128C

DSPE-PEG(2000) Amine

Da-Wen Dong et al.
Biomaterials, 34(20), 4849-4859 (2013-04-02)
A nanocarrier delivery system that can simultaneously deliver a chemotherapeutic drug and siRNA to the tumor is emerging as a promising treatment strategy for cancer treatment. In this study, a multifunctional PHD/PPF/siRNA complexes was developed by one-step assembly of prefunctionalized
Dipanjan Pan et al.
Chemical communications (Cambridge, England), (19)(19), 2400-2401 (2003-11-01)
Shell cross-linked nanoparticles (SCKs) constitute a unique class of materials with amphiphilic core-shell morphology; SCKs are characterised by their structural integrity and available functionality to attach receptor-recognising or receptor-specific ligands on the shell surface and, therefore, hold great potential in
Hyuk Sang Yoo et al.
Journal of controlled release : official journal of the Controlled Release Society, 100(2), 247-256 (2004-11-17)
For folate-receptor-targeted anti-cancer therapy, doxorubicin aggregates in a nano-scale size were produced employing doxorubicin-polyethylene glycol-folate (DOX-PEG-FOL) conjugate. Doxorubicin and folate were respectively conjugated to alpha- and omega-terminal end group of a PEG chain. The conjugates assisted to form doxorubicin nano-aggregates
Sun Hwa Kim et al.
Langmuir : the ACS journal of surfaces and colloids, 21(19), 8852-8857 (2005-09-07)
Poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles with anionic surface charge were surface coated with cationic di-block copolymer, poly(L-lysine)-poly(ethylene glycol)-folate (PLL-PEG-FOL) conjugate, for enhancing their site-specific intracellular delivery against folate receptor overexpressing cancer cells. The PLGA nanoparticles coated with the conjugate were characterized

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