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Merck
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Key Documents

Altri documenti

860646

Sigma-Aldrich

1-Methyl-DL-tryptophan

97%

Sinonimo/i:

1-Methyl-DL-tryptophan, 1-Methyltryptophan, 2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, 2-Amino-3-(1-methyl-1H-indol-3-yl)propanoicacid, 2-Amino-3-(1-methylindol-3-yl)propanoic acid, DL-1-Methyltryptophan, N′-Methyl-DL-tryptophan

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About This Item

Formula empirica (notazione di Hill):
C12H14N2O2
Numero CAS:
26988-72-7
Peso molecolare:
218.25
Numero CE:
248-157-6
Numero MDL:
MFCD00005803
Codice UNSPSC:
12352100
ID PubChem:
24888516
NACRES:
NA.22

Livello qualitativo

100

Saggio

97%

Forma fisica

solid

Punto di fusione

250 °C (dec.) (lit.)

Stringa SMILE

Cn1cc(CC(N)C(O)=O)c2ccccc12

InChI

1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)
ZADWXFSZEAPBJS-UHFFFAOYSA-N

Categorie correlate

Applicazioni

1-Methyl-DL-tryptophan, a competitive inhibitor of indoleamine 2,3 dioxygenase-1 (IDO1), has been used to study inflammation-induced depression in mice and syncytial virus induced bronchiolitis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Motivational changes that develop in a mouse model of inflammation-induced depression are independent of indoleamine 2, 3 dioxygenase.
Vichaya, Elisabeth G et al.
Neuropsychopharmacology (2018)
Seung-Ha Yang et al.
Experimental & molecular medicine, 41(5), 315-324 (2009-03-25)
Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying mechanisms are not clear. In this study, we investigated the mechanisms of the immunoregulatory activity of MSCs on T cells. Irradiated MSCs co-cultured with either na?ve or pre-activated
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Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.
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