77386
2-Bromo-1-ethyl-pyridinium tetrafluoroborate
≥97.0% (T)
Sinonimo/i:
BEP
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About This Item
Prodotti consigliati
Livello qualitativo
Saggio
≥97.0% (T)
Forma fisica
crystals
Impiego in reazioni chimiche
reaction type: Coupling Reactions
Punto di fusione
103-107 °C
applicazioni
peptide synthesis
Gruppo funzionale
bromo
Stringa SMILE
F[B-](F)(F)F.CC[n+]1ccccc1Br
InChI
1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8;2-1(3,4)5/h3-6H,2H2,1H3;/q+1;-1
YJDXVQLBIAJTHP-UHFFFAOYSA-N
Descrizione generale
2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.
Applicazioni
2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:
- The synthesis of N-methylated peptides in solution and solid phase.
- The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.
Altre note
Coupling reagent for peptide synthesis; less racemization and faster reaction than with other reagents;e.g. BOP, PyBrOP, PyClU, BTFFH, CMBI
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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