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552151

Sigma-Aldrich

D-Glucose-13C6,1,2,3,4,5,6,6-d7

97 atom % D, 99 atom % 13C

Sinonimo/i:

Deuterated Glucose, Labeled Glucose, D-Glucose-13C6,C-d7, Dextrose-13C6,C-d7

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About This Item

Formula empirica (notazione di Hill):
13C6H5D7O6
Numero CAS:
Peso molecolare:
193.15
Numero MDL:
Codice UNSPSC:
12352209
ID PubChem:
NACRES:
NA.12

Purezza isotopica

99 atom % 13C
97 atom % D

Livello qualitativo

Saggio

99% (CP)

Forma fisica

powder

Attività ottica

[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)

tecniche

bio NMR: suitable
protein expression: suitable

Punto di fusione

150-152 °C (lit.)

Spostamento di massa

M+13

Stringa SMILE

[2H][13C](=O)[13C@]([2H])(O)[13C@@]([2H])(O)[13C@]([2H])(O)[13C@]([2H])(O)[13C]([2H])([2H])O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i1+1D,2+1D2,3+1D,4+1D,5+1D,6+1D
GZCGUPFRVQAUEE-VVZLUFAVSA-N

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Descrizione generale

D- Glucose is a monosaccharide (simple sugar). It is a vital source of energy for living organisms. It exists in a cyclic form, containing six carbon atoms. It is present naturally in all plants and fruits in free or bound state. It is synthesized by the process, gluconeogenesis, in the liver and kidney.

Azioni biochim/fisiol

D-Glucose is involved in the metabolic processes, such as glycolysis and Kreb′s cycle for the generation of adenosine triphosphates. It is stored in the form of glycogen in liver. D-Glucose moieties constitutes to form cellulose by β-1,4-glycosidic linkage.

Confezionamento

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Hydrolysis of cellulose to glucose by solid acid catalysts
Huang YB and Fu Y
Green Chemistry, 15(5), 1095-1111 (2013)
Carl Öster et al.
Science advances, 5(7), eaaw6756-eaaw6756 (2019-08-09)
Ion conduction through potassium channels is a fundamental process of life. On the basis of crystallographic data, it was originally proposed that potassium ions and water molecules are transported through the selectivity filter in an alternating arrangement, suggesting a "water-mediated"
Chaevien S Clendinen et al.
Analytical chemistry, 87(11), 5698-5706 (2015-05-02)
The many advantages of (13)C NMR are often overshadowed by its intrinsically low sensitivity. Given that carbon makes up the backbone of most biologically relevant molecules, (13)C NMR offers a straightforward measurement of these compounds. Two-dimensional (13)C-(13)C correlation experiments like
Shilpa Nargund et al.
Biotechnology progress, 31(5), 1179-1186 (2015-06-23)
(13)C-metabolic flux analysis was used to understand copper deficiency-related restructuring of energy metabolism, which leads to excessive lactate production in recombinant protein-producing CHO cells. Stationary-phase labeling experiments with U-(13)C glucose were conducted on CHO cells grown under high and limiting
Soumya P Behera et al.
Nature communications, 11(1), 5547-5547 (2020-11-05)
Methyl-NMR enables atomic-resolution studies of structure and dynamics of large proteins in solution. However, resonance assignment remains challenging. The problem is to combine existing structural informational with sparse distance restraints and search for the most compatible assignment among the permutations.

Articoli

Solid-state NMR on Larger Biomolecules; Sigma-Aldrich.com

Learn about monosaccharide biosynthesis and the metabolism of monosaccharides. A unit of a carbohydrate and the simplest form of a sugar, a monosaccharide cannot be hydrolyzed into a simpler compound.

We present an article about the hyperpolarization of 13C labeled metabolites, especially pyruvic acid, using dynamic nuclear polarization (DNP) that allows real-time magnetic resonance spectroscopy.

Review the 10 steps of glycolysis in the Embden-Meyerhof-Parnas glycolytic pathway. Easily compare reaction stages and buy the enzymes for your life science research.

Contenuto correlato

Protein structure provides valuable information that can be used to infer protein function. The study of protein structure and mapping of protein interactions, expression levels, and location enables the identification of disease biomarkers and potential drug targets for therapeutic treatment.

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