534498
4-Piperidinopiperidine
97%
Sinonimo/i:
1,4′-Bipiperidine
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About This Item
Prodotti consigliati
Livello qualitativo
Saggio
97%
Punto di fusione
64-66 °C (lit.)
Temperatura di conservazione
−20°C
Stringa SMILE
C1CCN(CC1)C2CCNCC2
InChI
1S/C10H20N2/c1-2-8-12(9-3-1)10-4-6-11-7-5-10/h10-11H,1-9H2
QDVBKXJMLILLLB-UHFFFAOYSA-N
Informazioni sul gene
rat ... Grin2a(24409)
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Categorie correlate
Applicazioni
Reactant for synthesis of:
Arylthiadiazole H3 antagonists
Water-soluble N-mustards as anticancer agents
Antitubercular drugs
Vasopressin1b receptor antagonists
MDR modulators
Selective Norepinephrine transporter inhibitors
Arylthiadiazole H3 antagonists
Water-soluble N-mustards as anticancer agents
Antitubercular drugs
Vasopressin1b receptor antagonists
MDR modulators
Selective Norepinephrine transporter inhibitors
Medicinal chemistry reagent.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Gloves
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Synlett, 8, 1192-1194 (2003)
Journal of medicinal chemistry, 47(1), 101-109 (2003-12-30)
A variety of novel heterocyclic compounds having thienoazepine, pyrroloazepine, furoazepine, and thienodiazepine skeletons were synthesized, most of which exhibited potent antagonism of [(3)H]-AVP specific binding in assays using rat liver (V1), rat kidney (V2), human platelet plasma membranes, and recombinant
European journal of medicinal chemistry, 38(3), 265-275 (2003-04-02)
New antiprotozoals active against Philasterides dicentrarchi, the causative agent of scuticociliatosis in farmed turbot and Black Sea bass-bream, have been synthesised and tested. The most active compounds posses a piperazine ring, generally N-bonded to the heterocycle, and are the 1,8-naphthyridines
Design and synthesis of RNA-specific groove-binding cations: implications for antiviral drug design.
Journal of medicinal chemistry, 37(8), 1063-1069 (1994-04-15)
As as initial step in the design of structure-specific RNA-interactive molecules as potential antiviral agents, we have focused on the synthesis of molecules that exhibit strong and preferential binding to duplex RNA. A series of polycationic ligands have been synthesized
Bioorganic & medicinal chemistry, 13(19), 5592-5599 (2005-08-09)
We have synthesized a conjugate of cis-4,7,10,13,16,19-docosahexenoic acid (DHA) and 10-hydroxycamptothecin (HCPT), DHA-HCPT. The antitumor activity of DHA-HCPT was evaluated in vitro against L1210 leukemia cells and in experimental animal tumor models including L1210 leukemia, Lewis lung carcinoma, and colon
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