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317691

Sigma-Aldrich

Allyl disulfide

technical grade, 80%

Sinonimo/i:

Diallyl disulfide

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About This Item

Formula condensata:
CH2=CHCH2SSCH2CH=CH2
Numero CAS:
2179-57-9
Peso molecolare:
146.27
Beilstein:
1699241
Numero CE:
218-548-6
Numero MDL:
MFCD00008656
Codice UNSPSC:
12352100
ID PubChem:
24859096
NACRES:
NA.22

Grado

technical grade

Livello qualitativo

100

Densità del vapore

>5 (vs air)

Tensione di vapore

1 mmHg ( 20 °C)

Saggio

80%

Stato

liquid

Indice di rifrazione

n20/D 1.541 (lit.)

P. ebollizione

180-195 °C (lit.)

Densità

1.008 g/mL at 25 °C (lit.)

Gruppo funzionale

disulfide

Temperatura di conservazione

2-8°C

Stringa SMILE

C=CCSSCC=C

InChI

1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2
PFRGXCVKLLPLIP-UHFFFAOYSA-N

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Azioni biochim/fisiol

Organosulfur compound that is naturally found in garlic. Contributes to the pungent odor of crushed garlic. Anticancer agent and may provide protection against cardiovascular disease.

Altre note

Remainder other allyl sulfides

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301,H315,H319,H335

Classi di pericolo

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

143.6 °F - closed cup

Punto d’infiammabilità (°C)

62 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
SHBL9118
SHBL9119
MKCF8258
MKCB4951
MKBW2934V

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Nathaniel Edward Bennett Saidu et al.
Bioorganic & medicinal chemistry, 20(4), 1584-1593 (2012-01-24)
Coumarins and coumarin derivatives as well as diallyl polysulfides are well known as anticancer drugs. In order to find new drugs with anticancer activities, we combined coumarins with polysulfides in the form of di-coumarin polysulfides. These novel compounds were tested
Hailin Tang et al.
Cancer letters, 340(1), 72-81 (2013-07-16)
The purpose of this study was to identify a mechanism related to miRNA pathway which plays a role in the anti-tumor effects of Diallyl disulfide. Alterations in miRNA expression were observed in Diallyl disulfide-treated MGC-803 cells, including up-regulation of miR-200b
Hye Young Park et al.
Toxicology and applied pharmacology, 262(2), 177-184 (2012-05-09)
Diallyl disulfide (DADS), a main organosulfur component responsible for the diverse biological effects of garlic, displays a wide variety of internal biological activities. However, the cellular and molecular mechanisms underlying DADS' anti-inflammatory activity remain poorly understood. In this study, therefore
R Arunkumar et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(10), 912-923 (2012-06-29)
Diallyl Disulfide (DADS) is one of the major components of garlic, which inhibits the proliferation of various cancer cells. Our previous studies showed that DADS inhibits cell growth and induces apoptosis on prostate cancer cells. Insulin like growth factor signaling
Fenja Klevenhusena et al.
Archives of animal nutrition, 65(4), 255-266 (2011-09-06)
Currently research on feed supplementation with natural compounds to improve energy and protein utilisation and to mitigate the greenhouse gas methane in ruminants is intensively pursued. Two compounds, diallyl disulphide (DADS), an important component of garlic oil, and lovastatin, an
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