283746
4-(Aminomethyl)benzoic acid
97%, for peptide synthesis
Sinonimo/i:
PAMBA
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About This Item
Formula condensata:
H2NCH2C6H4CO2H
Numero CAS:
Peso molecolare:
151.16
Beilstein:
1100606
Numero CE:
Numero MDL:
Codice UNSPSC:
12352106
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Nome del prodotto
4-(Aminomethyl)benzoic acid, 97%
Saggio
97%
Stato
powder
Impiego in reazioni chimiche
reaction type: solution phase peptide synthesis
Punto di fusione
≥300 °C (lit.)
applicazioni
peptide synthesis
Stringa SMILE
NCc1ccc(cc1)C(O)=O
InChI
1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)
QCTBMLYLENLHLA-UHFFFAOYSA-N
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Categorie correlate
Applicazioni
4-(Aminomethyl)benzoic acid (PAMBA) can be used in the synthesis of:
- Cobalt carboxy phosphonates.
- Apoptozole (Az), which has cellular potency to promote membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel activity.
- Cyclopeptide composed of L-glutamic acid and 3-aminobenzoic acid that can be used as receptors for a variety of cations and anions.
- A bioactive peptide which has potent GPR54 (a G protein-coupled receptor) agonistic activity.
Altre note
4-(Aminomethyl)benzoic acid is also an antihemorrhagic agent, which is used for the treatment of internal haemorrhage.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Gloves
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Sandra Osburn et al.
Rapid communications in mass spectrometry : RCM, 21(21), 3409-3419 (2007-09-29)
Formation of [bn+17+cat]+ is a prominent collision-induced dissociation (CID) pathway for Li+- and Na+-cationized peptides. Dissociation of protonated and Ag+-cationized peptides instead favors formation of the rival bn+/[bn-1+cat]+ species. In this study the influence of a 4-aminomethylbenzoic acid (4AMBz) residue
E M Gorskaia et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 87-90 (1995-01-01)
The possibility of the correction of intestinal microflora disorders and the functional activity of macrophages in dysbiosis, caused by the intragastric administration of ampiox, with the use of amben (PAMBA), an inhibitor of proteolytic enzymes, was studied. Quantitative and qualitative
Carlos F R A C Lima et al.
The journal of physical chemistry. A, 111(42), 10598-10603 (2007-10-05)
The standard (p0 = 0.1 MPa) molar enthalpies of combustion of six aminomethylbenzoic acids were measured at T = 298.15 K by static bomb calorimetry. With these values, the standard molar enthalpies of formation in the crystalline state were obtained.
M N Iakushenko et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 77-79 (1998-04-09)
The examination of 49 newborn infants revealed that at the early neonatal period the character of the microbial colonization of the intestine depended on the kind of perinatal pathology: in lesions of the central nervous system and conjugation jaundice the
G A Chalyĭ et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 62-65 (1993-01-01)
The influence of protease-inhibiting preparations on the development of humoral immune response in diseases involving the development of secondary immunodeficiency (experimentally induced acute pancreatitis and staphylococcal infection) has been studied. Five injections of contrycal and epsilon-aminocaproic acid (epsilon-ACA), starting from
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