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Key Documents

Altri documenti

26569

Sigma-Aldrich

2-Chlorotrityl chloride

≥97.0% (AT)

Sinonimo/i:

Chloro(2-chlorophenyl)diphenylmethane

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About This Item

Formula empirica (notazione di Hill):
C19H14Cl2
Numero CAS:
42074-68-0
Peso molecolare:
313.22
Beilstein:
1983914
Numero CE:
255-647-3
Numero MDL:
MFCD00040399
Codice UNSPSC:
12352100
ID PubChem:
57648180
NACRES:
NA.22

Saggio

≥97.0% (AT)

Forma fisica

solid

Punto di fusione

130-135 °C

Stringa SMILE

Clc1ccccc1C(Cl)(c2ccccc2)c3ccccc3

InChI

1S/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H
JFLSOKIMYBSASW-UHFFFAOYSA-N

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Applicazioni

2-Chlorotrityl chloride was used to obtain protected peptide fragments that can be applied to the preparation of head-to-tail cyclopeptides or to condensation of peptidic fragments.

Altre note

Protecting group reagent for carboxylic acids forming esters which are cleaved mildly.

Pittogrammi

CorrosionExclamation mark
GHS05,GHS07

Avvertenze

Warning

Indicazioni di pericolo

H290,H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Sigma-Aldrich

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Evaluation of Ga-DOTA-(D-Asp)
Kazuma Ogawa et al.
Scientific reports, 7(1), 13971-13971 (2017-10-27)
Asker Y Khapchaev et al.
Journal of peptide science : an official publication of the European Peptide Society, 22(11-12), 673-681 (2016-10-05)
Myosin light chain kinase (MLCK) is a key regulator of various forms of cell motility including smooth muscle contraction, cell migration, cytokinesis, receptor capping, secretion, etc. Inhibition of MLCK activity in endothelial and epithelial monolayers using cell-permeant peptide Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys (PIK
Jie Luo et al.
Journal of the American Society for Mass Spectrometry, 30(9), 1643-1653 (2019-06-07)
Chemical cross-linking combined with mass spectrometry (CL-MS) is a powerful method for characterizing the architecture of protein assemblies and for mapping protein-protein interactions. Despite its proven utility, confident identification of cross-linked peptides remains a formidable challenge, especially when the peptides
Sogol Kangarlou et al.
Pharmaceutical biology, 55(1), 277-285 (2016-12-13)
Curcumin, a naturally occurring polyphenol, has been extensively studied for its broad-spectrum anticancer effects. The potential benefits are, however, limited due to its poor water solubility and rapid degradation which result in low bioavailability on administration. This study encapsulates curcumin
Elżbieta Kamysz et al.
Journal of peptide science : an official publication of the European Peptide Society, 18(9), 560-566 (2012-07-13)
LL37 and histatin 5 are antimicrobial peptides. LL37 exhibits killing activity against a broad spectrum of pathogens, whereas histatin 5 is primarily an antifungal agent. Head-to-tail cyclization of histatin 5 did not affect its antimicrobial and haemolytic activity. The cyclic
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