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247871

Sigma-Aldrich

2-Hydroxy-5-nitrobenzoic acid

99%

Sinonimo/i:

5-Nitrosalicylic acid, Anilotic acid

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About This Item

Formula condensata:
HOC6H3(NO2)CO2H
Numero CAS:
96-97-9
Peso molecolare:
183.12
Beilstein:
2213719
Numero CE:
202-548-8
Numero MDL:
MFCD00007338
Codice UNSPSC:
12352100
ID PubChem:
24854897
NACRES:
NA.22

Livello qualitativo

100

Saggio

99%

Punto di fusione

228-230 °C (lit.)

Solubilità

water: soluble 1g in 1475ml(lit.)
alcohol: freely soluble(lit.)
diethyl ether: freely soluble(lit.)
hot water: soluble(lit.)

Gruppo funzionale

carboxylic acid
nitro

Stringa SMILE

OC(=O)c1cc(ccc1O)[N+]([O-])=O

InChI

1S/C7H5NO5/c9-6-2-1-4(8(12)13)3-5(6)7(10)11/h1-3,9H,(H,10,11)
PPDRLQLKHRZIJC-UHFFFAOYSA-N

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Descrizione generale

2-Hydroxy-5-nitrobenzoic acid inhibits the activity of wild type-bovine low Mr protein tyrosine phosphatase. The inhibition constant has been evaluated.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
BCBX0957
BCBT3154
BCBT0212
BCBD9172V
07619ED

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Sigma-Aldrich

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Journal of the American Society for Mass Spectrometry, 29(7), 1473-1483 (2018-04-21)
Radical-driven dissociation (RDD) of hydrogen-deficient peptide ions [M - H + H]·+ has been examined using matrix-assisted laser dissociation/ionization in-source decay mass spectrometry (MALDI-ISD MS) with the hydrogen-abstracting matrices 4-nitro-1-naphthol (4,1-NNL) and 5-nitrosalicylic acid (5-NSA). The preferential fragment ions observed in the ISD spectra
M Zhou et al.
Biochemistry, 38(9), 2636-2646 (1999-03-03)
Pyridoxal 5'-phosphate (PLP) binds tightly to bovine low Mr protein tyrosine phosphatase (BPTP), but it is a very poor substrate for the enzyme. The structural basis of this tight binding of PLP is examined here by a variety of methods.
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Free radical biology & medicine, 108, 715-724 (2017-05-06)
Mesalazine (5-aminosalicylic acid, 5-ASA), a currently used drug for anti-inflammatory bowel disease, is easily oxidized by HOCl, a strong oxidant generated in gut inflammation, to produce electrophilic quinones. We investigated whether this chemical feature has an implication in the anti-inflammatory
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Proceedings of the National Academy of Sciences of the United States of America, 112(32), 9978-9983 (2015-07-29)
We present a proof of concept study designed to support the clinical development of mass spectrometry imaging (MSI) for the detection of pituitary tumors during surgery. We analyzed by matrix-assisted laser desorption/ionization (MALDI) MSI six nonpathological (NP) human pituitary glands
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Rapid communications in mass spectrometry : RCM, 34(10), e8722-e8722 (2020-01-09)
Hyphenation of atmospheric pressure chemical ionization (APCI) mass spectrometry with capillary and micro high-performance liquid chromatography (HPLC) is attractive for many applications, but reliable ion sources dedicated to these conditions are still missing. There are a number of aspects to

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