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226351

Sigma-Aldrich

N-Hydroxymaleimide

97%, for peptide synthesis

Sinonimo/i:

1-Hydroxypyrrole-2,5-dione

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About This Item

Formula empirica (notazione di Hill):
C4H3NO3
Numero CAS:
4814-74-8
Peso molecolare:
113.07
Beilstein:
1524594
Numero CE:
225-385-4
Numero MDL:
MFCD00005501
Codice UNSPSC:
12352005
ID PubChem:
24853562
NACRES:
NA.22

product name

N-Hydroxymaleimide, 97%

Livello qualitativo

200

Saggio

97%

Forma fisica

solid

Impiego in reazioni chimiche

reaction type: Addition Reactions

Punto di fusione

130-133 °C (dec.) (lit.)

applicazioni

peptide synthesis

Gruppo funzionale

imide
maleimide

Stringa SMILE

ON1C(=O)C=CC1=O

InChI

1S/C4H3NO3/c6-3-1-2-4(7)5(3)8/h1-2,8H
BUXKULRFRATXSI-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

N-Hydroxymaleimide (NHMI) is an organic compound that is widely used as an oxidizing agent in organic synthesis. It is frequently used to selectively oxidize thiols to disulfides and in the synthesis of α, β-unsaturated carbonyl compounds. It can also act as a Michael acceptor and is used in the synthesis of peptides and proteins.

Applicazioni

N-Hydroxymaleimide can be used as an oxidant to generate N-hydroxy anilines in situ, which serve as key intermediates in the selective coupling reaction of N-substituted anilines with hydroxylamine derivatives, for the efficient synthesis of aromatic oximes.

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H314

Classi di pericolo

Eye Dam. 1 - Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
BCCC3003
BCBW0273
BCBH2786V
1451856V
1451856

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