21860

CDI

≥97.0% (T), for peptide synthesis

• Sinonimo/i: 1,1′-Carbonyldiimidazole
• Formula empirica (notazione di Hill): C₇H₆N₄O
• Numero CAS: 530-62-1
• Peso molecolare: 162.15
• Beilstein: 6826
• Numero CE: 208-488-9
• Numero MDL: MFCD00005286
• Codice UNSPSC: 12352115
• ID PubChem: 57647944
• NACRES: NA.22

Proprietà

• product name: CDI, ≥97.0% (T)
• Livello qualitativo: 200
• Saggio: ≥97.0% (T)
• Forma fisica: solid
• Impiego in reazioni chimiche: reaction type: Carbonylations
• Punto di fusione: 115-122 °C; 117-122 °C (lit.)
• applicazioni: peptide synthesis
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O=C(n1ccnc1)n2ccnc2
• InChI: 1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H; PFKFTWBEEFSNDU-UHFFFAOYSA-N

Descrizione

Descrizione generale

CDI serves as a powerful coupling reagent in peptide synthesis and organic chemistry.

Applicazioni

CDI (1,1′-Carbonyldiimidazole) can be used:

• In the activation of malonic acid derivatives to prepare carbonyl imidazoles by mild decarboxylation.
• In the activation of cellulose membranes for the development of immunosensors.
• In the synthesis of substituted 1,3-oxazolo[4,5-d] pyridazinones.
• As a reagent for the conversion of various hydroxamic acids to isocyanates by Lossen rearrangement.
• In the synthesis of 1,3,4-oxadiazole derivatives , and peptide thioesters in water.
• As an acylation agent for the synthesis of carbamates.

Altre note

Reactive reagent for the activation of acids as imidazolides: synthesis of esters, amides, ketones etc. Reagent for immobilizing enzymes and affinity ligands; Carbonyl-transfer reagent for the synthesis of various heterocycles, some recent applications

Informazioni sulla sicurezza

• Pittogrammi: GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H314
• Consigli di prudenza: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Codice della classe di stoccaggio: 8A - Combustible corrosive hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges