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191906

Sigma-Aldrich

Hydroxypropyl cellulose

average Mw ~1,000,000, powder, 20 mesh particle size (99% through)

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About This Item

Numero CAS:
9004-64-2
Numero MDL:
MFCD00132688
Codice UNSPSC:
12162002
NACRES:
NA.23

Descrizione

biological oxygen demand (BOD) 14,000 ppm

Forma fisica

powder

Temp. autoaccensione

752 °F

PM

average Mw ~1,000,000

Impurezze

<5 wt. %

Dimensione particelle

20 mesh (99% through)

pH

5.0-8.5

Tensione interfacciale olio minerale

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

Viscosità

1,275-3,500 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #3) (30 rpm)(lit.)

Solubilità

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

Densità

0.5 g/mL at 25 °C (lit.)

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3
RRHXDYJWVYFMKV-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

  • Thermo-responsive aqueous foams: Hydroxypropyl cellulose has been studied for its properties as a green polymer that can alter its solubility with temperature changes, making it suitable for responsive foam applications (Braunschweig, 2019).
  • Interaction mechanism in aqueous solutions: A study on the interaction between hydroxypropyl cellulose and water in solutions, focusing on the importance of polymer chain length in determining the physical properties of the solutions (Martin-Pastor and Stoyanov, 2020).
  • Corrosion inhibition: Hydroxypropyl cellulose has shown effectiveness as a corrosion inhibitor for aluminium in acidic environments, highlighting its potential in material science and engineering applications (Nwanonenyi et al., 2019).
  • Orally disintegrating films: This application involves the formulation design of hydroxypropyl cellulose films, aiming to enhance the delivery and dissolution profile of pharmaceuticals, making it significant in drug delivery and pharmaceutical sciences (Takeuchi et al., 2018).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Satomi Onoue et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 492-499 (2012-04-14)
The present study was undertaken to develop a solid self-emulsifying drug delivery system of coenzyme Q(10) (CoQ(10)/s-SEDDS) with high photostability and oral bioavailability. The CoQ(10)/s-SEDDS was prepared by spray-drying an emulsion preconcentrate containing CoQ(10), medium-chain triglyceride, sucrose ester of fatty
Alexandre Monteiro et al.
Drug development and industrial pharmacy, 39(2), 266-283 (2012-04-17)
Nanoparticles of BCS Class II drugs are produced in wet stirred media mills operating in batch or recirculation mode with the goal of resolving the poor water-solubility issue. Scant information is available regarding the continuous production of drug nanoparticles via
Maya Fujiwara et al.
Chemical & pharmaceutical bulletin, 60(11), 1380-1386 (2012-11-06)
We evaluated models for predicting spray mist diameter suitable for scaling-up the fluidized bed granulation process. By precise selection of experimental conditions, we were able to identify a suitable prediction model that considers changes in binder solution, nozzle dimension, and
Ranjit M Dhenge et al.
International journal of pharmaceutics, 438(1-2), 20-32 (2012-09-11)
The present work focuses on the study of the progression of granules in different compartments along the length of screws in a twin screw granulator (TSG). The effects of varying powder feed rate; liquid to solid ratio and viscosity of
Hyemin Choi et al.
Journal of pharmaceutical sciences, 101(8), 2941-2951 (2012-05-26)
Living organisms secrete minerals composed of peptides and proteins, resulting in "mesocrystals" of three-dimensional-assembled composite structures. Recently, this biomimetic polymer-directed crystallization technique has been widely applied to inorganic materials, although it has seldom been used with drugs. In this study
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