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Merck
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Documenti

191892

Sigma-Aldrich

Hydroxypropyl cellulose

average Mw ~370,000, powder, 20 mesh particle size (99% through)

Sinonimo/i:

HPC

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About This Item

Numero CAS:
9004-64-2
Numero MDL:
MFCD00132688
Codice UNSPSC:
12162002
NACRES:
NA.23

Descrizione

biological oxygen demand (BOD) 14,000 ppm

Forma fisica

powder

Temp. autoaccensione

752 °F

PM

average Mw ~370,000

Impurezze

<5 wt. %

Dimensione particelle

20 mesh (99% through)

pH

5.0-8.5

Tensione interfacciale olio minerale

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

Viscosità

150-400 cP, 2 wt. % in H2O(25 °C, Brookfield, spindle #2) (60 rpm)(lit.)

Solubilità

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

Densità

0.5 g/mL at 25 °C (lit.)

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3
RRHXDYJWVYFMKV-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Hydroxypropyl cellulose (HPC) is a nonionic derivativeof cellulose. It is a thermosensitive, biodegradable polymer with low criticalsolution temperature.

Applicazioni

Hydroxypropyl cellulose can be used to prepare composite nanospheres for drug delivery systems. Hydroxypropyl methacrylate/hydroxy cellulose graft copolymers can be used as matrices for controlled-release tablets. It can also be used as an electrolyte additive to prepare gel polymerelectrolytes for dye-sensitized solar cells.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Satomi Onoue et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 492-499 (2012-04-14)
The present study was undertaken to develop a solid self-emulsifying drug delivery system of coenzyme Q(10) (CoQ(10)/s-SEDDS) with high photostability and oral bioavailability. The CoQ(10)/s-SEDDS was prepared by spray-drying an emulsion preconcentrate containing CoQ(10), medium-chain triglyceride, sucrose ester of fatty
Jianjun Yang et al.
International orthopaedics, 37(3), 515-521 (2012-11-28)
The aim of this study was to determine whether hydroxypropylcellulose (HPC) coating of polyethylene terephthalate (PET) artificial ligaments enhances graft osseointegration in the bone tunnel. Thirty New Zealand white rabbits underwent artificial ligament graft transplantation in the bilateral proximal tibia
Alexandre Monteiro et al.
Drug development and industrial pharmacy, 39(2), 266-283 (2012-04-17)
Nanoparticles of BCS Class II drugs are produced in wet stirred media mills operating in batch or recirculation mode with the goal of resolving the poor water-solubility issue. Scant information is available regarding the continuous production of drug nanoparticles via
Ranjit M Dhenge et al.
International journal of pharmaceutics, 438(1-2), 20-32 (2012-09-11)
The present work focuses on the study of the progression of granules in different compartments along the length of screws in a twin screw granulator (TSG). The effects of varying powder feed rate; liquid to solid ratio and viscosity of
Hyemin Choi et al.
Journal of pharmaceutical sciences, 101(8), 2941-2951 (2012-05-26)
Living organisms secrete minerals composed of peptides and proteins, resulting in "mesocrystals" of three-dimensional-assembled composite structures. Recently, this biomimetic polymer-directed crystallization technique has been widely applied to inorganic materials, although it has seldom been used with drugs. In this study
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