KEAP1
kelch-like ECH-associated protein 1
INrf2, KLHL19
Human KEAP1 (9817), Mouse Keap1 (50868), Rat Keap1 (117519), fruit fly Keap1 (42062), cow KEAP1 (532791), dog KEAP1 (476713), domestic cat KEAP1 (101091260), sheep KEAP1 (101113845), domestic guinea pig Keap1 (100713871), naked mole-rat Keap1 (101718777)
- Human(9817) Summary: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(50868) kelch-like ECH-associated protein 1
- Rat(117519) Kelch-like ECH-associated protein 1
- fruit fly(42062) CG3962 gene product from transcript CG3962-RC
- cow(532791) kelch-like ECH-associated protein 1
- dog(476713) kelch-like ECH-associated protein 1
- domestic cat(101091260) kelch-like ECH-associated protein 1
- sheep(101113845) kelch-like ECH-associated protein 1
- domestic guinea pig(100713871) kelch-like ECH-associated protein 1
- naked mole-rat(101718777) kelch-like ECH-associated protein 1
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Antibodies
Anti-Keap1 Antibody, clone 144, clone 144, from rat,
human, mouse
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-KEAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-KEAP1 (AB1) antibody produced in rabbit, affinity isolated antibody,
bovine, dog, horse, human, mouse, pig, rabbit, rat
immunohistochemistry
western blot
western blot
Anti-KEAP1 antibody produced in rabbit, IgG fraction of antiserum,
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
immunohistochemistry
western blot
western blot
Anti-KEAP1 Antibody, from rabbit, purified by affinity chromatography,
human, mouse, rat
immunocytochemistry
western blot
western blot
Small Molecule - Inhibitor
Dimethyl fumarate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
human