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Merck

GSTM1

glutathione S-transferase mu 1

Sinonimi:
GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1
Specie:
Human GSTM1 (2944), Mouse Gstm1 (14862), Rat Gstm1 (24423), cow GSTM1 (327709), cow GSTM1 (783879), domestic guinea pig Gstm1 (100731426)
ID UniProtKB:
P09488, Q5GHG0, Q6FH88, Q8TC98, Q9UC96
ID gene:
  • Human(2944) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14862) glutathione S-transferase, mu 1
  • Rat(24423) glutathione S-transferase mu 1
  • cow(327709) glutathione S-transferase M1
  • cow(783879) glutathione S-transferase mu 1
  • domestic guinea pig(100731426) glutathione S-transferase mu 1

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ELISA

N° Catalogo
Descrizione
Specie
RAB1496
Human GSTM1 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
HPA048652
Anti-GSTM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
SAB5700272
Anti-GSTM1 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot
HPA055972
Anti-GSTM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
HPA055973
Anti-GSTM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
WH0002944M1
Monoclonal Anti-GSTM1 antibody produced in mouse, clone 3B10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA

Cell Lines

N° Catalogo
Descrizione
Specie
GS65
GST M1-1, Recombinant Human, ,
Specie
human

Kits

N° Catalogo
Descrizione
Specie
CS0410
Glutathione-S-Transferase (GST) Assay Kit, sufficient for 500 multiwell tests,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU115801
MISSION® esiRNA, targeting human GSTM1,
Specie
human