BACE1
beta-site APP-cleaving enzyme 1
Sinonimi:
ASP2, BACE, HSPC104
Specie:
Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Zebrafish bace1 (403005), cow BACE1 (614333), Horse BACE1 (100071137), domestic cat BACE1 (101086840), dog BACE1 (489390), chicken BACE1 (419768), sheep BACE1 (101119667) ...Più
ID UniProtKB:
ID gene:
- Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- Mouse(23821) beta-site APP cleaving enzyme 1
- Rat(29392) beta-site APP cleaving enzyme 1
- Zebrafish(403005) beta-site APP-cleaving enzyme 1
- cow(614333) beta-site APP-cleaving enzyme 1
- Horse(100071137) beta-site APP-cleaving enzyme 1
- domestic cat(101086840) beta-site APP-cleaving enzyme 1
- dog(489390) beta-site APP-cleaving enzyme 1
- chicken(419768) beta-site APP-cleaving enzyme 1
- sheep(101119667) beta-site APP-cleaving enzyme 1
- Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
- naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
- domestic guinea pig(100135485) beta-site APP cleaving enzyme 1
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ELISA
N° Catalogo
Descrizione
Specie
Activity Assay
N° Catalogo
Descrizione
Specie
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Specie
human
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-BACE1 Antibody, clone 3D5, ,
Reattività con
human, mouse
Applicazione
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anticorpo anti-BACE, CT, clone 61-3E7, clone 61-3E7, Chemicon®, from mouse,
Reattività con
human, mouse, primate, rat
Applicazione
immunoprecipitation (IP)
western blot
western blot
Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
microarray
western blot
western blot
Anti-BACE1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
N° Catalogo
Descrizione
Specie
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Specie
human
Proteins
N° Catalogo
Descrizione
Specie
β-Secretase human, recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000 units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution,
Specie
human