跳转至内容
Merck
  • The effect of intraarticular levobupivacaine and bupivacaine injection on the postoperative pain management in total knee artroplastic surgery.

The effect of intraarticular levobupivacaine and bupivacaine injection on the postoperative pain management in total knee artroplastic surgery.

Pakistan journal of medical sciences (2015-02-13)
Nurcan Yavuz, Vildan Taspinar, Derya Karasu, Aysu Tezcan, Bayazit Dikmen, Nermin Gogus
摘要

Total knee arthroplasty (TKA) is associated with considerable postoperative pain. We compared the effects of intraoperative intraarticular levobupivacaine and bupivacaine on postoperative analgesia and analgesic consumption after total knee arthroplasty. Sixty ASA (American Society of Anesthesiologists) physical status II-III, 18-75 years old patients scheduled for unilateral TKA were included in this study. For the operative procedure combined spinal epidural anesthesia was given by injecting 15mg levobupivacaine in subarachnoid space at L3-4/L4- 5 in sitting position for all patients. In Group L 20ml levobupivacaine(0.5%), in Group B 20ml bupivacaine (0.5%) was injected intraarticularly 10 minutes before opening of the tourniquet at the end of the surgery. For all patients postoperative analgesia was provided with PCEA (levobupivacaine+fentanyl) and oral 1gr paracetamol four times a day. Patients' intraoperative-postoperative hemodynamical data, postoperative sensorial-motor block characteristics, side effects, PCEA demand ratios and bolus volumes, total analgesic consumption, VAS values, first mobilization time, hospitalization time were recorded. Statistical analysis was performed with SPSS version 13.00 software. There was no intergroup difference in demographic data, hemodynamical data, PCEA demand ratios, total analgesic consumption, first mobilization time, hospitalization time and VAS values at 0,2,72 hour. Postoperative lower VAS values were determined at 4,8,12,24 hours in Group B and at 48(th) hour in Group L(p<0.05). Intraarticular local anesthetic administration in addition to PCEA for post operative pain relief provides good analgesia after TKA surgery.

材料
货号
品牌
产品描述

Sigma-Aldrich
高氯酸, ACS reagent, 70%
Sigma-Aldrich
高氯酸, 70%, 99.999% trace metals basis
Sigma-Aldrich
高氯酸, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 70.0-72.0%
Sigma-Aldrich
高氯酸, ACS reagent, 60%
USP
Bupivacaine hydrochloride, United States Pharmacopeia (USP) Reference Standard
Sigma-Aldrich
高氯酸, 0.1 M
Sigma-Aldrich
高氯酸, puriss. p.a., ACS reagent, packed in coated, shock- and leak-protected glass bottle, ≥60% (T)
Supelco
布比卡因, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
高氯酸溶液, 0.01 M HClO4 in water (0.01N), eluent concentrate for IC
Supelco
布比卡因 盐酸盐, analytical standard, for drug analysis
布比卡因 盐酸盐, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
高氯酸, SAJ super special grade, 60.0-62.0%