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Merck

1672206

USP

托吡酯

United States Pharmacopeia (USP) Reference Standard

别名:

2,3: 双-4,5-O-(1-甲基亚乙基)-36--D -吡喃果糖氨基磺酸酯, McN 4853, RWJ 17021, 妥泰

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About This Item

经验公式(希尔记法):
C12H21NO8S
CAS号:
分子量:
339.36
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

topiramate

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

NS(OC[C@]12[C@](OC(C)(C)O2)([H])[C@@]3([H])[C@@](OC(C)(C)O3)([H])CO1)(=O)=O

InChI

1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1

InChI 密鑰

KJADKKWYZYXHBB-XBWDGYHZSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Topiramate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Topiramate Capsules
  • Topiramate Tablets
  • Topiramate Compounded Oral Suspension
Topiramate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Topiramate Tablets
  • Topiramate Compounded Oral Suspension

生化/生理作用

红藻氨酸 GluR5 受体拮抗剂;抗惊厥药。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Elizabeth M Kelly et al.
Journal of managed care pharmacy : JMCP, 19(8), 642-654 (2013-10-01)
Obesity may lead to the development of multiple chronic disease states, including hypertension, dyslipidemia, and type 2 diabetes mellitus. Over a half billion adults worldwide are affected by obesity, and more than two-thirds of adults are either obese or overweight
Glen L Xiong et al.
Postgraduate medicine, 126(2), 110-116 (2014-04-02)
The treatment of obesity is often met with a myriad of challenges in the primary care setting. Nevertheless, a modest 5% weight loss is considered clinically significant and may be associated with health benefits. Phentermine/topiramate (Qsymia), available in the United
Effects of Topiramate on afferent visual pathways: controversies and uncertainties.
Seyed-Hossein Abtahi et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 34(4), 603-604 (2012-05-23)
Fernando Sierra-Hidalgo et al.
Clinical neuropharmacology, 36(2), 63-64 (2013-03-19)
Palinopsia is an illusory visual phenomenon consisting in the persistence or recurrence of visual images after the exciting stimulus object has been removed. It has been reported in association with parietal and occipital lobe lesions, migraine auras, and related to
Vasiliki Katsi et al.
Recent patents on cardiovascular drug discovery, 8(1), 35-41 (2013-04-10)
Obesity is a major public health concern associated with increased morbidity and mortality. Its prevalence is rising worldwide mainly due to modern lifestyle habits. Several mechanisms like inflammation, endothelial dysfunction, increased sympathetic tone, high leptin and insulin concentrations as well

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