1642358

Sunitinib malate

United States Pharmacopeia (USP) Reference Standard

• 别名: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt, SU 011248, SU 11248, SU112248
• 经验公式（希尔记法）: C₂₂H₂₇FN₄O₂ · C₄H₆O₅
• CAS号: 341031-54-7
• 分子量: 532.56
• MDL號碼: MFCD08282795
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• agency: USP
• API 家族: sunitinib
• 包裝: pkg of 200 mg
• 製造商／商標名: USP
• 應用: pharmaceutical
• 形式: neat
• SMILES 字串: O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
• InChI: 1S/C22H27FN4O2.C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28;5-2(4(8)9)1-3(6)7/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28);2,5H,1H2,(H,6,7)(H,8,9)/b17-12-;/t;2-/m.0/s1
• InChI 密鑰: LBWFXVZLPYTWQI-IPOVEDGCSA-N

说明

一般說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

應用

Sunitinib malate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生化／生理作用

Sunitinib malate is a receptor tyrosine kinase inhibitor, which targets VEGF-R1, VEGF-R2, VEGF-R3, PDGF-Rα, PDGF-Rβ, KIT, FLT3, CSF-1R, and RET. Sunitinib malate is an anticancer drug.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H360,H372
• 防範說明: P202 - P260 - P264 - P280 - P308 + P313 - P405
• 危險分類: Repr. 1B - STOT RE 1 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable