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Merck
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文件

1586009

USP

溴吡斯的明

United States Pharmacopeia (USP) Reference Standard

别名:

3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide

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About This Item

经验公式（希尔记法）:
C9H13BrN2O2
CAS号:
101-26-8
分子量:
261.12
MDL號碼:
MFCD00079283
分類程式碼代碼:
41116107
PubChem物質ID:
329750870
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

pyridostigmine

製造商／商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

[Br-].CN(C)C(=O)Oc1ccc[n+](C)c1

InChI

1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1

InChI 密鑰

VNYBTNPBYXSMOO-UHFFFAOYSA-M

基因資訊

human ... ACHE(43)

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相关类别

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Pyridostigmine bromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Pyridostigmine Bromide Injection
  • Pyridostigmine Bromide Oral Solution
  • Pyridostigmine Bromide Tablets

生化／生理作用

Acetylcholinesterase inhibitor.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險分類

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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Alternating superior and inferior oblique myokymia.
Trevor A Smith et al.
JAMA ophthalmology, 132(7), 898-899 (2014-07-11)
P A Ferchmin et al.
Neurotoxicology, 44, 80-90 (2014-06-15)
Many organophosphorous esters synthesized for applications in industry, agriculture, or warfare irreversibly inhibit acetylcholinesterase, and acute poisoning with these compounds causes life-threatening cholinergic overstimulation. Following classical emergency treatment with atropine, an oxime, and a benzodiazepine, surviving victims often suffer brain
Marie Vandeput et al.
Journal of pharmaceutical and biomedical analysis, 102, 267-275 (2014-12-03)
A commercially available thin-layer flow-through amperometric detector, with the sensing block customized in an original design, was applied to the screening of drug compounds known as acetylcholinesterase (AChE) inhibitors. AChE from electric eel was covalently immobilized onto a cysteamine modified
Zuchra Zakirova et al.
PloS one, 10(3), e0119579-e0119579 (2015-03-19)
Gulf War Illness (GWI) is a chronic multisymptom illness with a central nervous system component such as memory deficits, neurological, and musculoskeletal problems. There are ample data that demonstrate that exposure to Gulf War (GW) agents, such as pyridostigmine bromide

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