1370462

氯沙坦钾

United States Pharmacopeia (USP) Reference Standard

• 别名: 2-丁基-4-氯-1-[[2′-(2H-四唑-5-基)[1,1′-联苯]-4-基]甲基]- 1H-咪唑-5-甲醇钾盐, 2-丁基-4-氯-1-{[2′-(1H-四唑-5-yl)(1,1′-联苯)-4-yl]甲基}-1H-咪唑-5-甲醇 单钾盐, DuP 753, MK 954, 钾5-(4′-((2-丁基-4-氯-5-(羟甲基)-1H-咪唑-1-基)甲基)-[1,1′-联苯]-2-yl)四唑-1-ide
• 经验公式（希尔记法）: C₂₂H₂₂ClKN₆O
• CAS号: 124750-99-8
• 分子量: 461.00
• Beilstein: 5845770
• MDL號碼: MFCD02092704
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329750264
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: losartan
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 形式: neat
• SMILES 字串: CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]
• InChI: 1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
• InChI 密鑰: OXCMYAYHXIHQOA-UHFFFAOYSA-N
• 基因資訊: human ... AGTR1(185)

说明

一般說明

Losartan potassium is a new drug used for hypertension. It is nonpeptide angiotensin II (AII) receptor antagonist.

Losartan potassium is nonpeptide angiotensin II (AII) receptor antagonist and is orally active. It belongs to a new class of drugs introduced for clinical trials to treat hypertension.

應用

Losartan potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Losartan Potassium and Hydrochlorothiazide Tablets
• Losartan Potassium Tablets

生化／生理作用

口服、强效、选择性的竞争血管紧张素II受体1型 (AT1)拮抗剂。

氯沙坦钾是一种口服、强效、选择性的竞争血管紧张素II受体1型 (AT1)拮抗剂。氯沙坦钾用于治疗高血压。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable