1302101

Guanfacine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• 别名: N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
• 经验公式（希尔记法）: C₉H₉Cl₂N₃O · HCl
• CAS号: 29110-48-3
• 分子量: 282.55
• MDL號碼: MFCD00798230
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329749977
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: guanfacine
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 格式: neat
• SMILES 字串: Cl.NC(=N)NC(=O)Cc1c(Cl)cccc1Cl
• InChI: 1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H
• InChI 密鑰: DGFYECXYGUIODH-UHFFFAOYSA-N
• 基因資訊: human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

• Reduction of Anxiety-related Reactivity in Primates: Guanfacine hydrochloride mediates anxiety-related reactivity and reduces associated agonistic behavior in two pigtail macaques, showcasing its potential for managing stress and aggression in clinical and veterinary settings (Hopper et al., 2024).


• Enhanced Analgesia for Surgical Procedures: The synergistic interaction of guanfacine with lidocaine enhances cutaneous analgesia, indicating its utility in improving pain management strategies, particularly in surgical environments (Chou et al., 2024).

生化／生理作用

α-2 noradrenergic receptor agonist.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 儲存類別代碼: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable