推荐产品
生物源
synthetic (organic)
品質等級
化驗
≥98% (HPLC)
形狀
powder
溶解度
water: 50 mg/mL, clear, colorless
儲存溫度
−20°C
SMILES 字串
OC[C@H]1O[C@H]([C@@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI
1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7+,8-/m1/s1
InChI 密鑰
DRTQHJPVMGBUCF-CCXZUQQUSA-N
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一般說明
阿糖尿苷(1-β-d-arabinofuranosyluracil, Ara-U)是阿糖胞苷 (1-β-d-arabinofuranosylcytosin, Ara-C) 的解毒产物或代谢产物。阿糖尿苷(Uracil 1-β-D-arabinofuranoside)是一种名为阿糖胞苷 (CYT) 的细胞生长抑制剂的人体代谢物。
應用
阿糖尿苷(Uracil 1-β-D-arabinofuranoside)可用作通过亲水相互作用色谱/串联质谱法分析医院废水细胞抑制剂和代谢物含量的标准化合物,检验分析实验的可行性和局限性。它还可用作化学分析标准品,研究细胞毒性抗肿瘤药物的生态毒性和遗传毒性,如阿糖胞苷 (CYT) 及其代谢物(如阿糖尿苷(uracil-1-β-d-arabinofuranoside, AraU))。
生化/生理作用
17 μM浓度的阿糖尿苷(1-β-D-Arabinofuranosyluracil, ara-U)能够抑制 L5178Y 小鼠淋巴瘤细胞增殖。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Metabolism of 1-beta-D-arabinofuranosyluracil in mouse L5178Y cells.
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[18F]FMAU is an established PET probe used to monitor cellular proliferation. For clinical applications, a fully automated cGMP-compliant radiosynthesis would be preferred. However, the current synthesis of [18F]FMAU requires HBr activation of the sugar prior to the coupling with silylated
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In this study, a novel technique for the preparation of (125)I-5-trimethylstannyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) urail (FIAU) was developed, (125)I-FIAU biodistribution profile was detected in Kunming mice and the possibility of using FTAU radio-labeling for reporter gene imaging was explored. 5-trimethylstannyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) urail (FTAU) was
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Clevudine is a nucleoside analog reverse transcriptase inhibitor that exhibits potent antiviral activity against hepatitis B virus (HBV) without serious side effects. However, mitochondrial myopathy has been observed in patients with chronic HBV infection taking clevudine. Moreover, the development of
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Nihon rinsho. Japanese journal of clinical medicine, 69 Suppl 4, 512-514 (2011-11-22)
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