TRUECD

TrueGel3D Crosslinker

CD cell-degradable crosslinker

• 别名: Crosslinker
• 分類程式碼代碼: 12352207
• NACRES: NA.52

属性

• 運輸包裝: dry ice
• 儲存溫度: −20°C

说明

一般說明

CD cell-degradable crosslinker is comprised of conjugated peptide along with polyethylene glycol and thiol (SH) groups. The thiol groups form stable thioether bond with thiol-reactive groups of the polymers (Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran) and results in a stable hydrogel.

The conjugated peptide has matrix metalloprotease (MMP)-cleavage sites (Pro-Leu-Gly-Leu-Trp-Ala), which allows matrix metalloproteases (MMP1, MMP3, MMP7 and MMP9) to locally degrade the polymer network. It allows cells to spread and migrate within the gel if they express the indicated MMPs.

應用

TRUECD is used to crosslink PVA and dextran polymers to generate cell-degradable hydrogel

特點和優勢

MMP degradable

成分

TRUECD contains CD cell-degradable crosslinker lyophilized and water.

注意

Avoid prolong exposure of CD cell-degradable crosslinker to air

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3