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Merck

T1512

Sigma-Aldrich

四咪唑 盐酸盐

powder, ≥99% (TLC)

别名:

(±)-2,3,5,6-四氢-6-苯基咪唑并[2,1-b]噻唑 盐酸盐

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About This Item

经验公式(希尔记法):
C11H12N2S · HCl
CAS号:
分子量:
240.75
Beilstein:
4358989
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

product name

四咪唑 盐酸盐, phosphatase inhibitor

生物源

synthetic (organic)

品質等級

描述

alkaline phosphatase inhibitor

化驗

≥99% (TLC)

形狀

powder

mp

266-267 °C (lit.)

溶解度

water: 50 mg/mL, clear, colorless

SMILES 字串

Cl[H].C1CN2CC(N=C2S1)c3ccccc3

InChI

1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H

InChI 密鑰

LAZPBGZRMVRFKY-UHFFFAOYSA-N

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應用

四咪唑衍生物作为碱性磷酸酶抑制剂的结构-活性关系。
适于抑制各种哺乳动物碱性磷酸酶(例如,肝、肾、胎盘、骨和肿瘤)。肠道碱性磷酸酶仅受到轻微的抑制。

其他說明

外消旋形式的左旋咪唑。

相關產品

产品编号
说明
价格

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Kinetics and inhibition of alkaline phosphatases from canine tissues.
H Van Belle
Biochimica et biophysica acta, 289(1), 158-168 (1972-11-10)
Nicolas T Chartier et al.
Nature physics, 17(8), 920-925 (2021-11-16)
Oocytes are large cells that develop into an embryo upon fertilization1. As interconnected germ cells mature into oocytes, some of them grow-typically at the expense of others that undergo cell death2-4. We present evidence that in the nematode Caenorhabditis elegans
Karla Opperman et al.
Genetics, 199(2), 497-509 (2014-12-10)
The L1CAM family of cell adhesion molecules is a conserved set of single-pass transmembrane proteins that play diverse roles required for proper nervous system development and function. Mutations in L1CAMs can cause the neurological L1 syndrome and are associated with
Mariana G Simões et al.
BMC developmental biology, 14, 49-49 (2015-01-01)
Zebrafish are able to regenerate many of its tissues and organs after damage. In amphibians this process is regulated by nerve fibres present at the site of injury, which have been proposed to release factors into the amputated limbs/fins, promoting
Jing Yuan et al.
Nature chemical biology, 5(10), 765-771 (2009-09-08)
Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279 bioactive chemicals. Hundreds of compounds were

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