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生物源
mouse
重組細胞
expressed in CHO cells
籤條
FLAG® tagged
化驗
>95% (SDS-PAGE)
形狀
lyophilized
分子量
~47 kDa by SDS-PAGE
包裝
pkg of 10 μg
儲存條件
avoid repeated freeze/thaw cycles
雜質
<0.01 EU/μg endotoxin, tested
顏色
white
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
mouse ... Serpinf1(20317)
一般說明
Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.
外觀
Lyophilized from PBS.
重構
Reconstitute with 100 μL deionized water.
其他說明
Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag.
法律資訊
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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