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Merck
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Key Documents

SRP8048

Sigma-Aldrich

PEDF mouse

recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)

别名:

Caspin, PC cell-derived growth factor, Pigment epithelium-derived factor, Stromal cell-derived factor 3

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

mouse

重組細胞

expressed in CHO cells

籤條

FLAG® tagged

化驗

>95% (SDS-PAGE)

形狀

lyophilized

分子量

~47 kDa by SDS-PAGE

包裝

pkg of 10 μg

儲存條件

avoid repeated freeze/thaw cycles

雜質

<0.01 EU/μg endotoxin, tested

顏色

white

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

一般說明

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

外觀

Lyophilized from PBS.

重構

Reconstitute with 100 μL deionized water.

其他說明

Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag.

法律資訊

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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