SML3811

Hygromycin A

≥98% (HPLC)

• 别名: Totomycin, 5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-D-neo-inositol, Homomycin, Hygromycin
• 经验公式（希尔记法）: C₂₃H₂₉NO₁₂
• CAS号: 6379-56-2
• 分子量: 511.48
• 分類程式碼代碼: 51111800
• 分類程式碼代碼: 12352200
• NACRES: NA.21

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C
• SMILES 字串: O[C@H]1[C@]2([H])[C@@]([C@@H]([C@@H]([C@@H]1O)NC(/C(C)=C/C3=CC=C(C(O)=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]4O)O)C(C)=O)=O)O)([H])OCO2
• InChI: 1S/C23H29NO12/c1-8(22(32)24-13-14(27)16(29)21-20(15(13)28)33-7-34-21)5-10-3-4-12(11(26)6-10)35-23-18(31)17(30)19(36-23)9(2)25/h3-6,13-21,23,26-31H,7H2,1-2H3,(H,24,32)/b8-5+/t13-,14+,15-,16-,17+,18+,19-,20+,21-,23-/m1/s1
• InChI 密鑰: YQYJSBFKSSDGFO-IIHALWDASA-N

说明

生化／生理作用

An orally available antibiotic; selectively taken up by nucleoside transporter specific to spirochete bacteria including Borreliella burgdorferi

Hygromycin A is an orally available antibiotic produced by Streptomyces hygroscopicus that targets the ribosomal 23S rRNA. Hygromycin A is selectively taken up by nucleoside transporter specific to spirochete bacteria including Borreliella burgdorferi, which causes Lyme disease. It clears B. burgdorferi infection in mice with lesser disruption of micron=biome than clinical antibiotics.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable