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SML3677

Sigma-Aldrich

Cryosim-3

≥98% (HPLC)

别名:

1-Di(isopropyl)phosphinoyl-nonane, 1-Diisopropylphosphorylnonane, Bis(1-methylethyl)nonylphosphine oxide, DIPA 1-9

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About This Item

经验公式（希尔记法）:
C15H33OP
CAS号:
1507344-37-7
分子量:
260.40
分類程式碼代碼:
12352200
NACRES:
NA.25

品質等級

100

化驗

≥98% (HPLC)

形狀

oil

顏色

colorless to yellow

儲存溫度

2-8°C

SMILES 字串

O=P(C(C)C)(C(C)C)CCCCCCCCC

InChI 密鑰

DHOTYMJGZIUWRT-UHFFFAOYSA-N

生化／生理作用

Cryosim-3 is a water soluble, selective and potent agonist of TRPM8 (transient receptor potential melastatin 8) receptor. Cryosim-3 increases tear secretion in an animal model of dry eye disease. Also it relieves ocular discomfort in subjects diagnosed with DED without eye irritation.
Water soluble, selective and potent agonist of TRPM8 receptor

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ying Yin et al.
Science (New York, N.Y.), 378(6616), eadd1268-eadd1268 (2022-10-14)
The transient receptor potential melastatin 8 (TRPM8) channel is the primary molecular transducer responsible for the cool sensation elicited by menthol and cold in mammals. TRPM8 activation is controlled by cooling compounds together with the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2).

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