SML3014

KL101

≥98% (HPLC)

• 别名: N-(2-(2,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-3,4-dimethyl-benzamide
• 经验公式（希尔记法）: C₂₂H₂₃N₃OS
• CAS号: 396721-89-4
• 分子量: 377.50
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: CC1=CC=C(C(NC2=C(CSC3)C3=NN2C4=C(C)C=C(C)C=C4)=O)C=C1C
• InChI: 1S/C22H23N3OS/c1-13-5-8-20(16(4)9-13)25-21(18-11-27-12-19(18)24-25)23-22(26)17-7-6-14(2)15(3)10-17/h5-10H,11-12H2,1-4H3,(H,23,26)

说明

生化／生理作用

KL101 is a circadian clock modulator that lengthens a circadian period in cells and tissues. It selectively stabilizes CRY1 through interaction with FAD-binding pocket. KL101 strongly enhanced brown adipocyte differentiation in culture. KL101 showed no or only minor effects on CKIδ, CKIα and CK2 activities in vitro.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable