SML2319
TAT-Gap19 trifluoroacetate salt
≥95% (HPLC)
别名:
L-Tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-glutaminyl-L-isoleucyl-L-?-glutamyl-L-isoleucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-lysine trifluoroacetate salt, YGRKKRRQRRRKQIEIKKFK trifluoroacetate salt
登录查看公司和协议定价
所有图片(1)
About This Item
经验公式（希尔记法）:
C119H212N46O26 · xC2HF3O2
CAS号:
分子量:
2703.25 (free base basis)
分類程式碼代碼:
12352200
NACRES:
NA.77
推荐产品
化驗
≥95% (HPLC)
形狀
lyophilized powder
顏色
white to off-white
運輸包裝
wet ice
儲存溫度
−20°C
生化／生理作用
TAT-Gap19 is a cell penetrant analog of a connexin 43 (Cx43) hemichannels selective blocker Gap19. TAT-Gap19 inhibits TAT-Gap19 in mice brain without affecting gap junction channels.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Verónica Abudara et al.
Frontiers in cellular neuroscience, 8, 306-306 (2014-11-07)
In the brain, astrocytes represent the cellular population that expresses the highest amount of connexins (Cxs). This family of membrane proteins is the molecular constituent of gap junction channels and hemichannels that provide pathways for direct cytoplasm-to-cytoplasm and inside-out exchange
Paolo Bazzigaluppi et al.
Neurobiology of disease, 101, 1-7 (2016-12-23)
Extracellular potassium concentration, [K+]o, is a major determinant of neuronal excitability. In the healthy brain, [K+]o levels are tightly controlled. During seizures, [K+]o increases up to 15mM and is thought to cause seizures due to its depolarizing effect. Although astrocytes
Laura Walrave et al.
Frontiers in cellular neuroscience, 10, 288-288 (2017-01-10)
Astrocytes are active players in higher brain function as they can release gliotransmitters, which are essential for synaptic plasticity. Various mechanisms have been proposed for gliotransmission, including vesicular mechanisms as well as non-vesicular ones, for example by passive diffusion via
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门