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化驗
≥95% (HPLC)
形狀
lyophilized
成份
Peptide Content, ≥80%
儲存條件
protect from light
儲存溫度
−20°C
基因資訊
human ... CASP9(842)
Amino Acid Sequence
Ac-Leu-Glu-His-Asp-al
生化／生理作用
Ac-Leu-Glu-His-Asp-al, or Ac-LEHD-CHO, is a cell-permeable tetrapeptide aldehyde. It is an inhibitor of caspase-9. Its target of action has been proposed to be the mitochondrial pathway of apoptosis. Ac-LEHD-CHO has also been postulated to prevent cleavage of caspase-8, and partly to prevent cleavage of caspase-3.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Daniel Purich
The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads (2017)
PP2A mediates apoptosis or autophagic cell death in multiple
myeloma cell lines
myeloma cell lines
Hang Zhou
Oncotarget (2017)
Hang Zhou et al.
Oncotarget, 8(46), 80770-80789 (2017-11-09)
The crosstalk between apoptosis and autophagy contributes to tumorigenesis and cancer therapy. The process by which BetA (betulinic acid), a naturally occurring triterpenoid, regulates apoptosis and autophagy as a cancer therapy is unclear. In this study, we show for the
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