推荐产品
生物源
alpaca
品質等級
重組細胞
expressed in E. coli
共軛
unconjugated
抗體表格
affinity purified VHH antibody
無性繁殖
EB61, monoclonal
化驗
>95% (SDS-PAGE)
形狀
lyophilized solid
分子量
14.4 kDa
~15-18 kDa (SDS PAGE under reducing condition)
純化經由
immobilized metal affinity chromatography (IMAC)
物種活性
human
濃度
1 mg/mL
技術
ELISA: 1:1000-1:25000
immunofluorescence: 1:200-1:600
immunohistochemistry: 1:200-1:600
顏色
colorless
pH值
( in PBS, pH 7.4)
同型
VHH
Protein ID登錄號
UniProt登錄號
運輸包裝
ambient
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... EGFR(1956)
一般說明
EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. Growth factor receptors are involved not only in promoting the proliferation of normal cells but also in the aberrant growth of many types of human tumors. Over-expression of the EGFR gene occurs in carcinomas with and without gene amplification. EGFR and erbB-2 are particularly important in breast cancer because increased production or activation has been associated with poor prognosis. EGFR belongs to a family of growth factor receptors, which also includes ErbB-2/HER-2/neu, ErbB-3/HER-3/neu and ErbB-4/HER-4neu. EGFR can heterodimerize with each of the members of this family.
Single-domain antibody (sdAb), also called nano-antibody, is the variable region isolated from the antigen-binding variable domain (VHH) of camelid heavy-chain-only antibody. It lacks light chains and a first constant domain(CH1). This configuration confers a number of unique advantages over conventional monoclonal antibodies. The small size of just 15 kDa (2~4 nm), single-domain antibody is the smallest antigen-binding fragment that can easily penetrate tissues, allowing them to bind epitopes that are inacessible to conventional antibodies. These single-domain antibodies offer superior chemical and thermal stability and increased solubility than conventional antibodies. All our antibodies are tested to ensure the highest level of specificity, sensitivity and reproducibility.
Single-domain antibody (sdAb), also called nano-antibody, is the variable region isolated from the antigen-binding variable domain (VHH) of camelid heavy-chain-only antibody. It lacks light chains and a first constant domain(CH1). This configuration confers a number of unique advantages over conventional monoclonal antibodies. The small size of just 15 kDa (2~4 nm), single-domain antibody is the smallest antigen-binding fragment that can easily penetrate tissues, allowing them to bind epitopes that are inacessible to conventional antibodies. These single-domain antibodies offer superior chemical and thermal stability and increased solubility than conventional antibodies. All our antibodies are tested to ensure the highest level of specificity, sensitivity and reproducibility.
特異性
Human Epidermal Growth Factor Receptor 1 (HER1/EGFR)
免疫原
Recombinant human EGFR (Leu25-Ser645) protein
應用
ELISA, IHC,IF
包裝
50 µg per vial / 100 µg per vial
外觀
Affinity purified VHH single domain antibody lyophilized from PBS, pH7.9
重構
Reconstitute the lyophilized antibody with sterile deionized water or with 50% glycerol (ACS grade or better) to a stock solution of 1 mg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
儲存和穩定性
Stable for 1 year at 4°C from date of receipt.
其他說明
Storage at 4°C; Do not freeze.
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门