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Merck
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Key Documents

SAB5702939

Sigma-Aldrich

Anti-Plectin Antibody, clone 9O0B3, Rabbit Monoclonal

别名:

EBS1, EBSMD, EBSND, EBSO, EBSOG, EBSPA, HD1, LGMD2Q, PCN, PLEC1, PLEC1b, PLTN

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

9O0B3, monoclonal

形狀

liquid

物種活性

rat, rat, human

濃度

1.20 mg/mL

技術

immunohistochemistry: 1:50 - 1:200

顏色

colorless

同型

IgG

免疫原序列

RTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTK

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... PLEC(5339)

一般說明

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types and tissues. As the expression of specific plectin isoforms was found to be dependent on cell type (tissue) and stage of development it appears that each cell type (tissue) contains a unique set (proportion and composition) of plectin isoforms, as if custom-made for specific requirements of the particular cells. Two other subtypes of plectin-related EBS have been described: EBS-pyloric atresia (PA) and EBS-Ogna.

免疫原

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 4401-4609 of human Plectin (NP_958782.1).

應用

IHC

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Aquatic Chronic 2 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3


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