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Merck
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Key Documents

SAB5702863

Sigma-Aldrich

Anti-TIMP1 Antibody, clone 5O7P1, Rabbit Monoclonal

别名:

CLGI, EPA, EPO, HCI, TIMP, TIMP-1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

5O7P1, monoclonal

形狀

liquid

分子量

26 kDa

物種活性

human

濃度

2 mg/mL

技術

western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSH

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TIMP1(7076)

一般說明

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TIMP1 (P01033).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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