SAB5702711

Anti-Tropomyosin 1 Antibody, clone 5Q2H6, Rabbit Monoclonal

• 别名: C15orf13, CMD1Y, CMH3, HEL-S-265, HTM-alpha, LVNC9, TMSA
• 分類程式碼代碼: 12352203

属性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 5Q2H6, monoclonal
• 形狀: liquid
• 分子量: 37 kDa
• 物種活性: mouse, rat
• 濃度: 0.3 mg/mL
• 技術: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: LSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
• UniProt登錄號: P09493
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... TPM1(7168)

说明

一般說明

This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 185-284 of human Tropomyosin 1 (P09493).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC, IF/ICC, IP

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1