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Merck

TPM1

tropomyosin 1 (alpha)

別名:
C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7168) Summary: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
  • Mouse(22003) tropomyosin 1, alpha
  • Rat(24851) tropomyosin 1, alpha
  • Zebrafish(393908) tropomyosin 1 (alpha)
  • domestic cat(101091450) tropomyosin 1 (alpha)
  • dog(478332) tropomyosin 1 (alpha)
  • chicken(396366) tropomyosin 1 (alpha)
  • cow(281544) tropomyosin 1 (alpha)
  • sheep(100145865) tropomyosin 1 (alpha)
  • domestic guinea pig(100717160) tropomyosin 1 (alpha)
  • naked mole-rat(101714552) tropomyosin 1 (alpha)

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗トロポミオシン抗体 ウサギ宿主抗体, whole antiserum,
交差性
chicken
アプリケーション
immunofluorescence
western blot
Anti-Tropomyosin Antibody, clone 15D12.2, clone 15D12.2, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-TPM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗TPM1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗TPM1抗体, IgG fraction of antiserum,
交差性
dog, guinea pig, human, mouse, rabbit, rat
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human TPM1,
Species
human
MISSION® esiRNA, targeting mouse Tpm1,
Species
mouse