SAB4700094

Monoclonal Anti-CD9-Biotin antibody produced in mouse

clone MEM-61, purified immunoglobulin, buffered aqueous solution

• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: mouse
• 共軛: biotin conjugate
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: MEM-61, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 濃度: 1 mg/mL
• 技術: flow cytometry: suitable
• 同型: IgG1
• NCBI登錄號: NM_001769.3
• UniProt登錄號: P21926
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CD9(928)

说明

一般說明

Cluster of differentiation 9 (CD 9) molecule, a member of transmembrane 4 super family (TM4SF) or tetraspanin superfamily, possesses four transmembrane domain. In human chromosome, the gene CD9 is localized on 12p13.31. The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

免疫原

Pre-B cell line NALM-6

應用

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1:400. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

生化／生理作用

Functions of cluster of differentiation 9 (CD9) molecule (CD9) include cell proliferation, activation, motility, and metastasis of tumor cells. CD9 along with CD81 is implicated to play a key role in muscle cell fusion and myotube maintenance. CD9 is associated with Interleukin 16 (IL-16) and induces migration and activation of mast cells. CD9 is involved in megakaryopoiesis. CD9 is expressed in Cord Blood CD34+ cells and might play a key role in hematopoietic stem cell (HSC) homing. CD9 associates with β1 integrin, membrane type 1−matrix metalloproteinase (MT1-MMP) and CD26 for HSC motility and homing. CD9 is crucial for sperm-egg fusion during fertilization. CD9 is a key molecule for glycoprotein 130 (gp130) mediated tumorigenic signal transduction in glioblastoma and a potential target for therapy.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable