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Merck
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Key Documents

SAB4503373

Sigma-Aldrich

Anti-TEAD2 antibody produced in rabbit

affinity isolated antibody

别名:

TEA domain family member 2, TEAD-2

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 49 kDa

物種活性

human, mouse

濃度

~1 mg/mL

技術

ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TEAD2(8463)

一般說明

TEA domain transcription factor 2 (TEAD2) belongs to the TEAD family. TEAD2 gene is located on human chromosome 19q13.3 Anti-TEAD2 antibody detects endogenous levels of total TEAD2 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human TEAD2.

Immunogen Range: 71-120

應用

Anti-TEAD2 antibody produced in rabbit has been used in western blotting.

生化/生理作用

TEA domain transcription factor 2 (TEAD2) plays a regulatory role in cell stemness. It modulates the expression of several genes. TEAD2 participates in the maintenance of cell survival. It is essential during neural development. TEAD2 might be a new therapeutic target and a predictive indicator of hepatocellular carcinoma (HCC).

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis.
P Jacquemin et al.
Genomics, 55(1), 127-129 (1999-01-16)
Jong Seok Joo et al.
Oncology reports, 43(6), 1785-1796 (2020-04-24)
TEA Domain Transcription Factors (TEADs) are important in development and serve essential roles in tumorigenesis; however, the role of TEAD2 expression in hepatocellular carcinoma (HCC) has not been widely examined. The present study was conducted to investigate the expression status
Kotaro J Kaneko et al.
Genesis (New York, N.Y. : 2000), 45(9), 577-587 (2007-09-18)
TEAD2, one of the first transcription factors expressed at the beginning of mammalian development, appears to be required during neural development. For example, Tead2 expression is greatest in the dorsal neural crest where it appears to regulate expression of Pax3
Paula González-Alonso et al.
Cancers, 12(5) (2020-05-06)
Trastuzumab is the first-line targeted therapeutic drug for HER2-positive breast cancer, leading to improved overall survival. However, acquired resistance inevitably occurs. We aimed to identify, quantify, and assess the mechanisms of acquired resistance to trastuzumab. We established an acquired trastuzumab-resistant

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