推荐产品
生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
26 kDa
物種活性
human, mouse
濃度
1 mg/mL
技術
immunohistochemistry: 1:10- 1:50
western blot: 1:500-1:2000 (Cell Lysate)
同型
IgG
登錄號
P00403
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... MT-CO2(4513)
一般說明
Mitochondrially encoded cytochrome c oxidase II (MT-CO2) is a key subunit of cytochrome c oxidase, which is the terminal enzyme involved in the oxidative phosphorylation complexes.
特異性
The antibody detects endogenous levels of total MT-CO2 protein.
免疫原
Synthetic peptide corresponding to a region derived from internal residues of human mitochondrially encoded cytochrome c oxidase II
生化/生理作用
Polymorphism in mitochondrially encoded cytochrome c oxidase II (MT-CO2) might alter electron transfer from cytochrome c to the bimetallic center of the catalytic subunit I. Aberrations in MT-CO2 expression has been observed in prostate cancer patients.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
A novel MT-CO2 m.8249G?>?A pathogenic variation and the MT-TW m.5521G?>?A mutation in patients with mitochondrial myopathy
Mitochondrial DNA, 25(5), 394-399 (2014)
Mitochondrial cytochrome c oxidase subunit II variations predict adverse prognosis in cytogenetically normal acute myeloid leukaemia.
European Journal of Haematology, 91(4), 295-303 (2013)
Altered expression of 12S/MT-RNR1, MT-CO2/COX2, and MT-ATP6 mitochondrial genes in prostate cancer.
Prostate, 68(10), 1086-1096 (2008)
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